HCSGD entry for THBS2
1. General information
| Official gene symbol | THBS2 |
|---|---|
| Entrez ID | 7058 |
| Gene full name | thrombospondin 2 |
| Other gene symbols | TSP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005604 | Basement membrane | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0016525 | Negative regulation of angiogenesis | IDA IEA | biological_process |
| GO:0051965 | Positive regulation of synapse assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2595722807 | 0.0006202652 | 0.9531317409 | 0.0464551136 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2763915812 |
| GSE13712_SHEAR | Down | -0.2370702110 |
| GSE13712_STATIC | Up | 0.1155117608 |
| GSE19018 | Down | -0.7457974723 |
| GSE19899_A1 | Up | 0.0940268619 |
| GSE19899_A2 | Down | -1.3697469556 |
| PubMed_21979375_A1 | Down | -2.0683904208 |
| PubMed_21979375_A2 | Down | -1.5816928539 |
| GSE35957 | Up | 0.7997685797 |
| GSE36640 | Down | -3.9038734105 |
| GSE54402 | Down | -1.9114299057 |
| GSE9593 | Down | -0.0944358320 |
| GSE43922 | Down | -0.4907876312 |
| GSE24585 | Down | -0.0237297976 |
| GSE37065 | Down | -0.6030023758 |
| GSE28863_A1 | Up | 1.1583424404 |
| GSE28863_A2 | Up | 1.0692094732 |
| GSE28863_A3 | Up | 0.5473043315 |
| GSE28863_A4 | Down | -0.5032200528 |
| GSE48662 | Up | 0.1299239098 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
