HCSGD entry for TG

1. General information

Official gene symbolTG
Entrez ID7038
Gene full namethyroglobulin
Other gene symbolsAITD3 TGN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIRDmolecular_function
GO:0005179Hormone activityIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005615Extracellular spaceIBA IEAcellular_component
GO:0005887Integral component of plasma membraneIRDcellular_component
GO:0006590Thyroid hormone generationIBAbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0007416Synapse assemblyIRDbiological_process
GO:0009986Cell surfaceIRDcellular_component
GO:0015705Iodide transportIEAbiological_process
GO:0030878Thyroid gland developmentIEPbiological_process
GO:0031641Regulation of myelinationIEAbiological_process
GO:0042043Neurexin family protein bindingIRDmolecular_function
GO:0042403Thyroid hormone metabolic processIEAbiological_process
GO:0042446Hormone biosynthetic processIEAbiological_process
GO:0045202SynapseIRDcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07435101630.98788743970.57869089301.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2174089078
GSE13712_SHEARUp0.3408772884
GSE13712_STATICDown-0.0007523496
GSE19018Up0.0859712920
GSE19899_A1Up0.1560908982
GSE19899_A2Up0.0989511185
PubMed_21979375_A1Up0.6594842268
PubMed_21979375_A2Up0.2069357986
GSE35957Down-0.1105143042
GSE36640Up0.2482939881
GSE54402Down-0.1159572520
GSE9593Up0.0528598292
GSE43922Up0.0954063164
GSE24585Up0.1883396394
GSE37065Up0.1540739662
GSE28863_A1Up0.0438891662
GSE28863_A2Up0.1694776845
GSE28863_A3Up0.1278965810
GSE28863_A4Up0.0801493126
GSE48662Up0.8171337901

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7f-5pMIMAT0000067MIRT032091qRT-PCRFunctional MTI (Weak)19956384
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.