HCSGD entry for TFR2
1. General information
| Official gene symbol | TFR2 |
|---|---|
| Entrez ID | 7036 |
| Gene full name | transferrin receptor 2 |
| Other gene symbols | HFE3 TFRC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004998 | Transferrin receptor activity | NAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006826 | Iron ion transport | NAS | biological_process |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0006898 | Receptor-mediated endocytosis | NAS | biological_process |
| GO:0008233 | Peptidase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8033001862 | 0.4677719008 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1226683965 |
| GSE13712_SHEAR | Down | -0.3201626359 |
| GSE13712_STATIC | Down | -0.0127126625 |
| GSE19018 | Up | 0.0215248928 |
| GSE19899_A1 | Up | 0.0324409836 |
| GSE19899_A2 | Up | 0.0961397621 |
| PubMed_21979375_A1 | Down | -0.4056340620 |
| PubMed_21979375_A2 | Down | -0.0369194893 |
| GSE35957 | Down | -0.2426668647 |
| GSE36640 | Down | -0.1627458113 |
| GSE54402 | Up | 0.1648381591 |
| GSE9593 | Up | 0.0463504265 |
| GSE43922 | Up | 0.0283893450 |
| GSE24585 | Down | -0.0311943952 |
| GSE37065 | Down | -0.0308029535 |
| GSE28863_A1 | Down | -0.2245596123 |
| GSE28863_A2 | Up | 0.0422682823 |
| GSE28863_A3 | Up | 0.3621924315 |
| GSE28863_A4 | Up | 0.0719068344 |
| GSE48662 | Up | 0.2766001094 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
