HCSGD entry for NR2F2

1. General information

Official gene symbolNR2F2
Entrez ID7026
Gene full namenuclear receptor subfamily 2, group F, member 2
Other gene symbolsARP1 COUPTFB COUPTFII NF-E3 NR2F1 SVP40 TFCOUP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0001893Maternal placenta developmentIEAbiological_process
GO:0001937Negative regulation of endothelial cell proliferationIMPbiological_process
GO:0001945Lymph vessel developmentIEAbiological_process
GO:0001972Retinoic acid bindingIDAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIC IDAmolecular_function
GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0004879Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006629Lipid metabolic processTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007519Skeletal muscle tissue developmentIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009566FertilizationIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0009956Radial pattern formationIEAbiological_process
GO:0010596Negative regulation of endothelial cell migrationIMPbiological_process
GO:0030522Intracellular receptor signaling pathwayIDA TASbiological_process
GO:0030900Forebrain developmentIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043565Sequence-specific DNA bindingIDA IEAmolecular_function
GO:0045736Negative regulation of cyclin-dependent protein serine/threonine kinase activityIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0048514Blood vessel morphogenesisIEAbiological_process
GO:0060173Limb developmentIEAbiological_process
GO:0060674Placenta blood vessel developmentIEAbiological_process
GO:0060707Trophoblast giant cell differentiationIEAbiological_process
GO:0060849Regulation of transcription involved in lymphatic endothelial cell fate commitmentIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94566832950.00766522550.99999024730.1751432292

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0938580645
GSE13712_SHEARDown-0.4416729951
GSE13712_STATICDown-0.1868241727
GSE19018Up0.2857141639
GSE19899_A1Down-0.3134580405
GSE19899_A2Down-0.7639455877
PubMed_21979375_A1Down-1.3241426814
PubMed_21979375_A2Down-1.4111594845
GSE35957Up0.2439261189
GSE36640Down-0.9630086183
GSE54402Down-0.0846547412
GSE9593Up0.3140185198
GSE43922Down-0.4248963993
GSE24585Down-0.4406199608
GSE37065Down-0.3499573329
GSE28863_A1Up0.0154516650
GSE28863_A2Down-0.3888382907
GSE28863_A3Up0.0788498073
GSE28863_A4Down-0.0208530970
GSE48662Down-0.0711192108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-302a-3pMIMAT0000684MIRT006555Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI21151097
hsa-miR-101-3pMIMAT0000099MIRT027270SequencingFunctional MTI (Weak)20371350
hsa-miR-935MIMAT0004978MIRT036667CLASHFunctional MTI (Weak)23622248
hsa-miR-877-5pMIMAT0004949MIRT037296CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.