HCSGD entry for NR2F1
1. General information
| Official gene symbol | NR2F1 |
|---|---|
| Entrez ID | 7025 |
| Gene full name | nuclear receptor subfamily 2, group F, member 1 |
| Other gene symbols | COUP-TFI EAR-3 EAR3 ERBAL3 NR2F2 SVP44 TCFCOUP1 TFCOUP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0003707 | Steroid hormone receptor activity | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0004879 | Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0010977 | Negative regulation of neuron projection development | IEA | biological_process |
| GO:0021796 | Cerebral cortex regionalization | IEA | biological_process |
| GO:0030522 | Intracellular receptor signaling pathway | TAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0044323 | Retinoic acid-responsive element binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6671902245 | 0.8605376164 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.3418662336 |
| GSE28863_A2 | Down | -0.0291478913 |
| GSE28863_A3 | Up | 0.4347384232 |
| GSE28863_A4 | Down | -0.1444591681 |
| GSE48662 | Up | 0.5143876435 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-149-5p | MIMAT0000450 | MIRT045568 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047264 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
