HCSGD entry for TMBIM6
1. General information
| Official gene symbol | TMBIM6 |
|---|---|
| Entrez ID | 7009 |
| Gene full name | transmembrane BAX inhibitor motif containing 6 |
| Other gene symbols | BAXI1 BI-1 TEGT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032469 | Endoplasmic reticulum calcium ion homeostasis | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0070059 | Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0335740511 | 0.9903869838 | 0.4214875060 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4088963482 |
| GSE13712_SHEAR | Up | 0.1049056190 |
| GSE13712_STATIC | Up | 0.0389031389 |
| GSE19018 | Up | 0.4899669644 |
| GSE19899_A1 | Up | 0.4666054719 |
| GSE19899_A2 | Up | 0.5366803032 |
| PubMed_21979375_A1 | Up | 0.3043438908 |
| PubMed_21979375_A2 | Up | 0.3952555479 |
| GSE35957 | Down | -0.1988315944 |
| GSE36640 | Up | 0.2118288618 |
| GSE54402 | Up | 0.0207287715 |
| GSE9593 | Up | 0.1974163844 |
| GSE43922 | Up | 0.2825568817 |
| GSE24585 | Up | 0.2023328294 |
| GSE37065 | Up | 0.0387233979 |
| GSE28863_A1 | Up | 0.1956899193 |
| GSE28863_A2 | Up | 0.1905179044 |
| GSE28863_A3 | Down | -0.2468739480 |
| GSE28863_A4 | Up | 0.1221077980 |
| GSE48662 | Up | 0.0398648455 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020530 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031401 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042252 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045127 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT050638 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord

