HCSGD entry for TCEB1

1. General information

Official gene symbolTCEB1
Entrez ID6921
Gene full nametranscription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Other gene symbolsSIII eloC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0030891VCB complexIEAcellular_component
GO:0032403Protein complex bindingIEAmolecular_function
GO:0032968Positive regulation of transcription elongation from RNA polymerase II promoterIEAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
GO:0061418Regulation of transcription from RNA polymerase II promoter in response to hypoxiaTASbiological_process
GO:0070449Elongin complexIEAcellular_component
GO:0071456Cellular response to hypoxiaTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24706366020.86935133920.93502708451.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1485263492
GSE13712_SHEARUp0.2443552717
GSE13712_STATICUp0.1334117388
GSE19018Down-0.2831399258
GSE19899_A1Up0.1627636159
GSE19899_A2Up0.3605664594
PubMed_21979375_A1Up0.1493801667
PubMed_21979375_A2Up0.4004264870
GSE35957Down-0.0436281817
GSE36640Up0.0923319912
GSE54402Up0.1138259928
GSE9593Up0.0699535656
GSE43922Up0.1547874218
GSE24585Down-0.1833689870
GSE37065Up0.0063768279
GSE28863_A1Down-0.1272125247
GSE28863_A2Up0.3104916861
GSE28863_A3Down-0.2284772922
GSE28863_A4Up0.0747292926
GSE48662Down-0.1619681314

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.