HCSGD entry for TCEA1
1. General information
| Official gene symbol | TCEA1 |
|---|---|
| Entrez ID | 6917 |
| Gene full name | transcription elongation factor A (SII), 1 |
| Other gene symbols | GTF2S SII TCEA TF2S TFIIS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006283 | Transcription-coupled nucleotide-excision repair | TAS | biological_process |
| GO:0006289 | Nucleotide-excision repair | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0030218 | Erythrocyte differentiation | IEA | biological_process |
| GO:0032784 | Regulation of DNA-templated transcription, elongation | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9080591809 | 0.1488965655 | 0.9999902473 | 0.7463543135 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1599385527 |
| GSE13712_SHEAR | Up | 0.0409608001 |
| GSE13712_STATIC | Down | -0.1054558775 |
| GSE19018 | Up | 0.2792716063 |
| GSE19899_A1 | Down | -0.1031085860 |
| GSE19899_A2 | Down | -0.2880956574 |
| PubMed_21979375_A1 | Down | -0.4156535519 |
| PubMed_21979375_A2 | Down | -0.2891116085 |
| GSE35957 | Down | -0.0537170844 |
| GSE36640 | Down | -0.2755499450 |
| GSE54402 | Down | -0.1744135264 |
| GSE9593 | Up | 0.0113248402 |
| GSE43922 | Down | -0.2891627122 |
| GSE24585 | Down | -0.0041073760 |
| GSE37065 | Down | -0.2232134002 |
| GSE28863_A1 | Up | 0.1400288751 |
| GSE28863_A2 | Down | -0.1636640555 |
| GSE28863_A3 | Down | -0.1304829297 |
| GSE28863_A4 | Up | 0.0004592348 |
| GSE48662 | Up | 0.5912318711 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020490 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-497-5p | MIMAT0002820 | MIRT041184 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050483 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
