HCSGD entry for SERPINA7

1. General information

Official gene symbolSERPINA7
Entrez ID6906
Gene full nameserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
Other gene symbolsTBG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIBAmolecular_function
GO:0005576Extracellular regionIBA NAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0007568AgingIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0010951Negative regulation of endopeptidase activityIBAbiological_process
GO:0030162Regulation of proteolysisIBAbiological_process
GO:0033189Response to vitamin AIEAbiological_process
GO:0034695Response to prostaglandin EIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042562Hormone bindingIEAmolecular_function
GO:0043434Response to peptide hormoneIEAbiological_process
GO:0051412Response to corticosteroneIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60344461080.78449804340.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0052230661
GSE13712_SHEARDown-0.1339472293
GSE13712_STATICDown-0.2201257722
GSE19018Down-0.0455147980
GSE19899_A1Up0.1052077244
GSE19899_A2Down-0.0731937005
PubMed_21979375_A1Up0.0856122452
PubMed_21979375_A2Up0.3116059128
GSE35957Up0.3691394234
GSE36640Down-0.0136812537
GSE54402Up0.0552445717
GSE9593Down-0.0261078243
GSE43922Up0.0200428183
GSE24585Up0.1900920678
GSE37065Up0.0706084568
GSE28863_A1Down-0.1014261844
GSE28863_A2Up0.0359569340
GSE28863_A3Up0.1115208839
GSE28863_A4Down-0.0612629265
GSE48662Down-0.0953844092

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.