HCSGD entry for TARBP2

1. General information

Official gene symbolTARBP2
Entrez ID6895
Gene full nameTAR (HIV-1) RNA binding protein 2
Other gene symbolsLOQS TRBP TRBP1 TRBP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003725Double-stranded RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006417Regulation of translationIEAbiological_process
GO:0006469Negative regulation of protein kinase activityTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016442RISC complexIDA IEAcellular_component
GO:0030422Production of siRNA involved in RNA interferenceIDA IEAbiological_process
GO:0030423Targeting of mRNA for destruction involved in RNA interferenceIMPbiological_process
GO:0031054Pre-miRNA processingIDA IEAbiological_process
GO:0035197SiRNA bindingIDA IEAmolecular_function
GO:0035198MiRNA bindingIEAmolecular_function
GO:0035280MiRNA loading onto RISC involved in gene silencing by miRNAIDA IEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0045070Positive regulation of viral genome replicationIDAbiological_process
GO:0046782Regulation of viral transcriptionIDA IEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050689Negative regulation of defense response to virus by hostIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62442392390.32329170620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3379381526
GSE13712_SHEARDown-0.3159711582
GSE13712_STATICDown-0.1602601712
GSE19018Up0.0301776319
GSE19899_A1Down-0.1425534993
GSE19899_A2Up0.4325729371
PubMed_21979375_A1Up0.3645501044
PubMed_21979375_A2Up0.2059509517
GSE35957Down-0.1781936734
GSE36640Down-0.0255237952
GSE54402Down-0.0098109124
GSE9593Down-0.5027237738
GSE43922Up0.0509175278
GSE24585Up0.0530556614
GSE37065Down-0.0035797364
GSE28863_A1Down-0.1172475924
GSE28863_A2Down-0.3457473715
GSE28863_A3Down-0.0478145922
GSE28863_A4Up0.0278464991
GSE48662Down-0.3416211251

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027513MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT029188MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.