HCSGD entry for TAF10

1. General information

Official gene symbolTAF10
Entrez ID6881
Gene full nameTAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
Other gene symbolsTAF2A TAF2H TAFII30
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000125PCAF complexIDAcellular_component
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004402Histone acetyltransferase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005669Transcription factor TFIID complexIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006352DNA-templated transcription, initiationIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIC TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterIC IDA TASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016578Histone deubiquitinationIDAbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0030331Estrogen receptor bindingIDAmolecular_function
GO:0030914STAGA complexIDAcellular_component
GO:0033276Transcription factor TFTC complexIDAcellular_component
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0051260Protein homooligomerizationIDAbiological_process
GO:0070063RNA polymerase bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98713474790.05494238820.99999024730.4422442202

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1573360839
GSE13712_SHEARDown-0.1164237265
GSE13712_STATICDown-0.1055963243
GSE19018Down-0.1316021665
GSE19899_A1Down-0.2646378457
GSE19899_A2Up0.1942886303
PubMed_21979375_A1Down-0.4091843433
PubMed_21979375_A2Up0.0127882463
GSE35957Down-0.2477047741
GSE36640Down-0.0000460236
GSE54402Down-0.0603536846
GSE9593Down-0.0999206370
GSE43922Down-0.2933038801
GSE24585Down-0.0908312373
GSE37065Down-0.0585602621
GSE28863_A1Down-0.4370337450
GSE28863_A2Down-0.3772455348
GSE28863_A3Down-0.3400807207
GSE28863_A4Down-0.1480699733
GSE48662Up0.2089704419

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-491-5pMIMAT0002807MIRT004657Luciferase reporter assayNon-Functional MTI20065103
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.