HCSGD entry for TAF7

1. General information

Official gene symbolTAF7
Entrez ID6879
Gene full nameTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
Other gene symbolsTAF2F TAFII55
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0000296Spermine transportISSbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005669Transcription factor TFIID complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006352DNA-templated transcription, initiationIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterIDAbiological_process
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0008024Positive transcription elongation factor complex bIDAcellular_component
GO:0008134Transcription factor bindingIPImolecular_function
GO:0030520Intracellular estrogen receptor signaling pathwayIEAbiological_process
GO:0033276Transcription factor TFTC complexIDAcellular_component
GO:0035035Histone acetyltransferase bindingIPImolecular_function
GO:0035067Negative regulation of histone acetylationIDAbiological_process
GO:0042809Vitamin D receptor bindingIPImolecular_function
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046966Thyroid hormone receptor bindingIPImolecular_function
GO:0071339MLL1 complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02105001330.90980501880.34978371211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2789154957
GSE13712_SHEARUp0.1698253146
GSE13712_STATICUp0.1810042076
GSE19018Up0.0637873489
GSE19899_A1Up0.6857232635
GSE19899_A2Up0.5337553635
PubMed_21979375_A1Up0.7002171569
PubMed_21979375_A2Up0.5470838317
GSE35957Up0.4929754935
GSE36640Up0.4924802362
GSE54402Up0.3617739556
GSE9593Up0.4234366303
GSE43922Up0.4522199048
GSE24585Up0.1028577425
GSE37065Up0.1615234650
GSE28863_A1Down-0.2252482111
GSE28863_A2Up0.0068111506
GSE28863_A3Down-1.2052828762
GSE28863_A4Down-0.1261277487
GSE48662Up0.1014506886

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-374b-5pMIMAT0004955MIRT016037SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.