HCSGD entry for TAF4
1. General information
| Official gene symbol | TAF4 |
|---|---|
| Entrez ID | 6874 |
| Gene full name | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa |
| Other gene symbols | TAF2C TAF2C1 TAF4A TAFII130 TAFII135 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001541 | Ovarian follicle development | IEA | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006352 | DNA-templated transcription, initiation | IDA IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0033276 | Transcription factor TFTC complex | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0071339 | MLL1 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4925721211 | 0.7078488127 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0352382872 |
| GSE13712_SHEAR | Up | 0.1188313916 |
| GSE13712_STATIC | Up | 0.1764957979 |
| GSE19018 | Down | -0.1339696165 |
| GSE19899_A1 | Up | 0.0631528614 |
| GSE19899_A2 | Up | 0.0896475215 |
| PubMed_21979375_A1 | Up | 0.6058917663 |
| PubMed_21979375_A2 | Up | 0.1822491367 |
| GSE35957 | Down | -0.1928551820 |
| GSE36640 | Down | -0.6259147854 |
| GSE54402 | Up | 0.0370839529 |
| GSE9593 | Up | 0.1454931832 |
| GSE43922 | Up | 0.0454614968 |
| GSE24585 | Down | -0.0361386900 |
| GSE37065 | Down | -0.0008095396 |
| GSE28863_A1 | Up | 0.1219085192 |
| GSE28863_A2 | Up | 0.0513115717 |
| GSE28863_A3 | Up | 0.2256785941 |
| GSE28863_A4 | Up | 0.0346675815 |
| GSE48662 | Down | -0.5729885919 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031295 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT047763 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048812 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
