HCSGD entry for TACC1
1. General information
| Official gene symbol | TACC1 |
|---|---|
| Entrez ID | 6867 |
| Gene full name | transforming, acidic coiled-coil containing protein 1 |
| Other gene symbols | Ga55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0021987 | Cerebral cortex development | IEA | biological_process |
| GO:0022008 | Neurogenesis | IEA | biological_process |
| GO:0022027 | Interkinetic nuclear migration | IEA | biological_process |
| GO:0032886 | Regulation of microtubule-based process | IEA | biological_process |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0645128567 | 0.9666872649 | 0.5478231935 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1073764364 |
| GSE13712_SHEAR | Down | -0.1000235942 |
| GSE13712_STATIC | Down | -0.1418168183 |
| GSE19018 | Up | 0.6396618989 |
| GSE19899_A1 | Up | 0.3725046074 |
| GSE19899_A2 | Up | 0.0747396857 |
| PubMed_21979375_A1 | Up | 0.0089755852 |
| PubMed_21979375_A2 | Up | 0.5325099326 |
| GSE35957 | Down | -0.1220281991 |
| GSE36640 | Up | 0.5706912202 |
| GSE54402 | Up | 0.0896397498 |
| GSE9593 | Up | 0.0945415456 |
| GSE43922 | Up | 0.1344289299 |
| GSE24585 | Up | 0.0880886538 |
| GSE37065 | Up | 0.0155749259 |
| GSE28863_A1 | Up | 0.2293918102 |
| GSE28863_A2 | Up | 0.7335210009 |
| GSE28863_A3 | Down | -0.0597140704 |
| GSE28863_A4 | Down | -0.0776652109 |
| GSE48662 | Down | -0.1554628913 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016082 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016576 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043593 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
