HCSGD entry for TACR2

1. General information

Official gene symbolTACR2
Entrez ID6865
Gene full nametachykinin receptor 2
Other gene symbolsNK2R NKNAR SKR TAC2R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004995Tachykinin receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0007217Tachykinin receptor signaling pathwayTASbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007588ExcretionTASbiological_process
GO:0014057Positive regulation of acetylcholine secretion, neurotransmissionIEAbiological_process
GO:0014827Intestine smooth muscle contractionIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016497Substance K receptor activityIEAmolecular_function
GO:0033685Negative regulation of luteinizing hormone secretionIEAbiological_process
GO:0035106Operant conditioningIEAbiological_process
GO:0043117Positive regulation of vascular permeabilityIEAbiological_process
GO:0070459Prolactin secretionIEAbiological_process
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23443037880.89632927320.91763380371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0585278241
GSE13712_SHEARUp0.0992654793
GSE13712_STATICDown-0.1633886689
GSE19018Down-0.0271541808
GSE19899_A1Up0.2176080217
GSE19899_A2Up0.2858915521
PubMed_21979375_A1Up0.1302218340
PubMed_21979375_A2Up0.0621830461
GSE35957Up0.0878710129
GSE36640Up0.3270844850
GSE54402Up0.0007866061
GSE9593Up0.0423005347
GSE43922Up0.0311286289
GSE24585Up0.0254834818
GSE37065Up0.1923733344
GSE28863_A1Down-0.1094492523
GSE28863_A2Down-0.1545269675
GSE28863_A3Up0.3537264017
GSE28863_A4Up0.0441913641
GSE48662Up0.3247741753

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017841MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.