HCSGD entry for SVIL
1. General information
| Official gene symbol | SVIL |
|---|---|
| Entrez ID | 6840 |
| Gene full name | supervillin |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002102 | Podosome | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007010 | Cytoskeleton organization | IEA | biological_process |
| GO:0007519 | Skeletal muscle tissue development | IMP | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA NAS | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0043034 | Costamere | IDA | cellular_component |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
| GO:0071437 | Invadopodium | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0041282626 | 0.9628227233 | 0.1730254777 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0830871751 |
| GSE13712_SHEAR | Up | 0.0510106671 |
| GSE13712_STATIC | Up | 0.0057201869 |
| GSE19018 | Up | 0.1489489346 |
| GSE19899_A1 | Up | 1.5397519274 |
| GSE19899_A2 | Up | 0.5073626308 |
| PubMed_21979375_A1 | Down | -0.4624682575 |
| PubMed_21979375_A2 | Up | 1.2498575412 |
| GSE35957 | Up | 0.5131003151 |
| GSE36640 | Up | 1.2761959129 |
| GSE54402 | Up | 0.6633287388 |
| GSE9593 | Up | 1.0829544103 |
| GSE43922 | Up | 0.8184268173 |
| GSE24585 | Down | -0.1945226848 |
| GSE37065 | Up | 0.1798620206 |
| GSE28863_A1 | Up | 0.1991907359 |
| GSE28863_A2 | Up | 0.4295578989 |
| GSE28863_A3 | Down | -0.1363750373 |
| GSE28863_A4 | Down | -0.0485163561 |
| GSE48662 | Down | -0.2392061701 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016778 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039692 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040980 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051583 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
