HCSGD entry for SUPT6H
1. General information
| Official gene symbol | SUPT6H |
|---|---|
| Entrez ID | 6830 |
| Gene full name | suppressor of Ty 6 homolog (S. cerevisiae) |
| Other gene symbols | SPT6 SPT6H emb-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0006338 | Chromatin remodeling | NAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0010793 | Regulation of mRNA export from nucleus | IEA ISS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016788 | Hydrolase activity, acting on ester bonds | IEA | molecular_function |
| GO:0032968 | Positive regulation of transcription elongation from RNA polymerase II promoter | IEA IMP | biological_process |
| GO:0042393 | Histone binding | IDA | molecular_function |
| GO:0045191 | Regulation of isotype switching | IEA ISS | biological_process |
| GO:0050684 | Regulation of mRNA processing | IEA ISS | biological_process |
| GO:0051028 | MRNA transport | IEA | biological_process |
| GO:0051147 | Regulation of muscle cell differentiation | IEA ISS | biological_process |
| GO:0061086 | Negative regulation of histone H3-K27 methylation | IEA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0023112876 | 0.9953886592 | 0.1288493697 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2080258195 |
| GSE13712_SHEAR | Up | 0.1893736372 |
| GSE13712_STATIC | Up | 0.0966178875 |
| GSE19018 | Down | -0.0203287928 |
| GSE19899_A1 | Up | 0.0576274899 |
| GSE19899_A2 | Up | 0.4368121178 |
| PubMed_21979375_A1 | Up | 1.6063919040 |
| PubMed_21979375_A2 | Up | 1.1173483582 |
| GSE35957 | Up | 0.2642207248 |
| GSE36640 | Up | 0.5793748176 |
| GSE54402 | Up | 0.4630081853 |
| GSE9593 | Up | 0.3182603188 |
| GSE43922 | Up | 0.1703900498 |
| GSE24585 | Up | 0.4183084770 |
| GSE37065 | Up | 0.0486098430 |
| GSE28863_A1 | Up | 1.2281765225 |
| GSE28863_A2 | Up | 1.0266296052 |
| GSE28863_A3 | Up | 0.1167084039 |
| GSE28863_A4 | Up | 0.0896135467 |
| GSE48662 | Up | 0.3180737212 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-652-3p | MIMAT0003322 | MIRT039536 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039964 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045937 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047722 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
