HCSGD entry for STXBP2

1. General information

Official gene symbolSTXBP2
Entrez ID6813
Gene full namesyntaxin binding protein 2
Other gene symbolsFHL5 Hunc18b MUNC18-2 UNC18-2 UNC18B pp10122
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001909Leukocyte mediated cytotoxicityIMPbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006904Vesicle docking involved in exocytosisIEAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0016324Apical plasma membraneIEAcellular_component
GO:0017075Syntaxin-1 bindingIEAmolecular_function
GO:0030348Syntaxin-3 bindingIEA IPImolecular_function
GO:0031201SNARE complexIDAcellular_component
GO:0042581Specific granuleIDAcellular_component
GO:0042582Azurophil granuleIDAcellular_component
GO:0043304Regulation of mast cell degranulationISSbiological_process
GO:0043312Neutrophil degranulationIEPbiological_process
GO:0044194Cytolytic granuleIDAcellular_component
GO:0070062Extracellular vesicular exosomeIDAcellular_component
GO:0070820Tertiary granuleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27950800120.93726084880.97636752881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0612301317
GSE13712_SHEARUp0.7870624841
GSE13712_STATICUp0.5703615155
GSE19018Up0.0126263793
GSE19899_A1Up0.0160502249
GSE19899_A2Up0.0008338688
PubMed_21979375_A1Down-0.1181356718
PubMed_21979375_A2Up0.2249079149
GSE35957Up0.1575747377
GSE36640Down-0.1032304251
GSE54402Down-0.0302525235
GSE9593Up0.0873533600
GSE43922Up0.0543141467
GSE24585Up0.0737607796
GSE37065Down-0.0752923326
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0067682175

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020657ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.