HCSGD entry for STX4
1. General information
| Official gene symbol | STX4 |
|---|---|
| Entrez ID | 6810 |
| Gene full name | syntaxin 4 |
| Other gene symbols | STX4A p35-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000149 | SNARE binding | IEA | molecular_function |
| GO:0005484 | SNAP receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005773 | Vacuole | TAS | cellular_component |
| GO:0005802 | Trans-Golgi network | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006836 | Neurotransmitter transport | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0016323 | Basolateral plasma membrane | IDA | cellular_component |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0031201 | SNARE complex | IDA | cellular_component |
| GO:0035749 | Myelin sheath adaxonal region | IEA | cellular_component |
| GO:0042581 | Specific granule | IDA | cellular_component |
| GO:0043219 | Lateral loop | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1329342806 | 0.8398412408 | 0.7380221894 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4243451972 |
| GSE13712_SHEAR | Up | 0.1090406870 |
| GSE13712_STATIC | Down | -0.0790586097 |
| GSE19018 | Up | 0.0695838108 |
| GSE19899_A1 | Up | 0.0688949212 |
| GSE19899_A2 | Up | 0.5104364490 |
| PubMed_21979375_A1 | Up | 0.7958108582 |
| PubMed_21979375_A2 | Down | -0.0165926518 |
| GSE35957 | Down | -0.4491885892 |
| GSE36640 | Up | 0.5376394504 |
| GSE54402 | Up | 0.4556527288 |
| GSE9593 | Down | -0.0046952282 |
| GSE43922 | Down | -0.0500855796 |
| GSE24585 | Down | -0.2066650888 |
| GSE37065 | Down | -0.0884144892 |
| GSE28863_A1 | Up | 0.0186580098 |
| GSE28863_A2 | Up | 0.1174150290 |
| GSE28863_A3 | Up | 0.3064954378 |
| GSE28863_A4 | Up | 0.2054133162 |
| GSE48662 | Down | -0.4045387862 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031473 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-22-3p | MIMAT0000077 | MIRT050473 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25412306 | We identified 107 proteins that could be potential markers of senescence and validated 10 of them (DEP1, NTAL, EBP50, STX4, VAMP3, ARMX3, B2MG, LANCL1, VPS26A and PLD3) |
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