HCSGD entry for SST

1. General information

Official gene symbolSST
Entrez ID6750
Gene full namesomatostatin
Other gene symbolsSMST
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005179Hormone activityTASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0006972Hyperosmotic responseIEAbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007584Response to nutrientTASbiological_process
GO:0007586DigestionTASbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0008628Hormone-mediated apoptotic signaling pathwayTASbiological_process
GO:0009408Response to heatIEAbiological_process
GO:0030334Regulation of cell migrationIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043200Response to amino acidIEAbiological_process
GO:0048545Response to steroid hormoneIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52626903610.75712488890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0467684478
GSE13712_SHEARUp0.0350980850
GSE13712_STATICDown-0.0037905127
GSE19018Down-0.0266211029
GSE19899_A1Up0.1309321414
GSE19899_A2Down-0.2581496761
PubMed_21979375_A1Down-0.2294347492
PubMed_21979375_A2Down-0.0877629200
GSE35957Up0.1218110793
GSE36640Up0.0286038223
GSE54402Up0.0708858981
GSE9593Up0.0199341292
GSE43922Up0.1602276343
GSE24585Up0.0960127751
GSE37065Up0.0087076642
GSE28863_A1Down-0.0885420945
GSE28863_A2Up0.2204725451
GSE28863_A3Up0.3932949171
GSE28863_A4Down-0.2005292609
GSE48662Down-0.0149478280

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

19342460Increased endogenous somatostatin (SST) tone may also slow the conversion from hyperplastic to adenomatous state because mRNA levels for SST receptors, sst2 and sst5, were elevated in hyperplastic pituitaries, whereas adenomas were associated with a decline in sst1 and sst5 mRNA
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