HCSGD entry for SSRP1
1. General information
| Official gene symbol | SSRP1 |
|---|---|
| Entrez ID | 6749 |
| Gene full name | structure specific recognition protein 1 |
| Other gene symbols | FACT FACT80 T160 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9244353824 | 0.0066872915 | 0.9999902473 | 0.1642558769 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2434408517 |
| GSE13712_SHEAR | Down | -0.5687511022 |
| GSE13712_STATIC | Down | -0.3716377489 |
| GSE19018 | Down | -0.1859412061 |
| GSE19899_A1 | Down | -0.3004328925 |
| GSE19899_A2 | Down | -0.9161681865 |
| PubMed_21979375_A1 | Down | -0.6190480505 |
| PubMed_21979375_A2 | Down | -1.3038958806 |
| GSE35957 | Down | -1.1794897149 |
| GSE36640 | Down | -2.5206168050 |
| GSE54402 | Up | 0.2800535263 |
| GSE9593 | Down | -0.8324211974 |
| GSE43922 | Down | -0.0165279303 |
| GSE24585 | Down | -0.3606883447 |
| GSE37065 | Down | -0.0752918781 |
| GSE28863_A1 | Up | 0.6420311835 |
| GSE28863_A2 | Up | 0.3327055979 |
| GSE28863_A3 | Up | 0.1177764684 |
| GSE28863_A4 | Up | 0.2347784009 |
| GSE48662 | Down | -0.4192402156 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036046 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040724 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041569 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046282 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050286 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050408 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050489 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3200-3p | MIMAT0015085 | MIRT052826 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26522327 | Inflammatory signal-mediated release of high-mobility group box 1 (HMGB1) is a damage-associated molecular pattern or alarmin |
| 23649808 | HMGB1 (high mobility group box 1) modulates gene expression in the nucleus, but certain immune cells secrete HMGB1 as an extracellular Alarmin to signal tissue damage |
| 15282327 | The phosphorylation of T160 of SRF by PKC delta in vitro and in vivo led to loss of SRF DNA binding activity |
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