HCSGD entry for SSR2
1. General information
| Official gene symbol | SSR2 |
|---|---|
| Entrez ID | 6746 |
| Gene full name | signal sequence receptor, beta (translocon-associated protein beta) |
| Other gene symbols | TLAP TRAP-BETA TRAPB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005783 | Endoplasmic reticulum | IEA TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006613 | Cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9250243874 | 0.1879408305 | 0.9999902473 | 0.8403593851 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2442625532 |
| GSE13712_SHEAR | Down | -0.2159296799 |
| GSE13712_STATIC | Down | -0.1196917155 |
| GSE19018 | Down | -0.1905911632 |
| GSE19899_A1 | Down | -0.0781136178 |
| GSE19899_A2 | Down | -0.2912946520 |
| PubMed_21979375_A1 | Down | -0.0842642867 |
| PubMed_21979375_A2 | Down | -0.4568909061 |
| GSE35957 | Down | -0.4209131366 |
| GSE36640 | Down | -0.2579269750 |
| GSE54402 | Up | 0.2356580031 |
| GSE9593 | Down | -0.0849780762 |
| GSE43922 | Up | 0.1419309031 |
| GSE24585 | Down | -0.0044102092 |
| GSE37065 | Down | -0.0236695987 |
| GSE28863_A1 | Up | 0.1533027786 |
| GSE28863_A2 | Up | 0.0112963567 |
| GSE28863_A3 | Down | -0.1654355189 |
| GSE28863_A4 | Down | -0.1173972910 |
| GSE48662 | Down | -0.4092053237 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040270 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-345-5p | MIMAT0000772 | MIRT042734 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042799 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045273 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045638 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
