HCSGD entry for SSR1
1. General information
| Official gene symbol | SSR1 |
|---|---|
| Entrez ID | 6745 |
| Gene full name | signal sequence receptor, alpha |
| Other gene symbols | TRAPA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006613 | Cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2807799134 | 0.3570162646 | 0.9782851264 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2906276312 |
| GSE13712_SHEAR | Down | -0.2265509667 |
| GSE13712_STATIC | Down | -0.0127906775 |
| GSE19018 | Down | -0.1699790273 |
| GSE19899_A1 | Up | 0.2507316685 |
| GSE19899_A2 | Down | -0.1581242645 |
| PubMed_21979375_A1 | Down | -0.4742976270 |
| PubMed_21979375_A2 | Up | 0.2662398887 |
| GSE35957 | Down | -0.2060290403 |
| GSE36640 | Up | 0.2946833786 |
| GSE54402 | Up | 0.0244479633 |
| GSE9593 | Down | -0.0165131290 |
| GSE43922 | Up | 0.0390602090 |
| GSE24585 | Up | 0.0065001310 |
| GSE37065 | Up | 0.0779735599 |
| GSE28863_A1 | Up | 0.6457795331 |
| GSE28863_A2 | Up | 0.6055754130 |
| GSE28863_A3 | Down | -0.8699405076 |
| GSE28863_A4 | Down | -0.2748445888 |
| GSE48662 | Down | -0.1784183414 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005046 | Microarray | Functional MTI (Weak) | 17699775 |
| hsa-miR-1 | MIMAT0000416 | MIRT024095 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT046983 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
