HCSGD entry for SRP68
1. General information
| Official gene symbol | SRP68 |
|---|---|
| Entrez ID | 6730 |
| Gene full name | signal recognition particle 68kDa |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005047 | Signal recognition particle binding | IEA IPI | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005786 | Signal recognition particle, endoplasmic reticulum targeting | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005840 | Ribosome | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | IEA TAS | biological_process |
| GO:0008312 | 7S RNA binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030942 | Endoplasmic reticulum signal peptide binding | IEA | molecular_function |
| GO:0042493 | Response to drug | IDA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1043708940 | 0.8931789028 | 0.6713456256 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2228517710 |
| GSE13712_SHEAR | Up | 0.3146735695 |
| GSE13712_STATIC | Up | 0.4985749142 |
| GSE19018 | Down | -0.0882849594 |
| GSE19899_A1 | Down | -0.2826301078 |
| GSE19899_A2 | Up | 0.1097219624 |
| PubMed_21979375_A1 | Up | 0.5793604391 |
| PubMed_21979375_A2 | Up | 0.4775085730 |
| GSE35957 | Down | -0.2417249596 |
| GSE36640 | Down | -0.1623066344 |
| GSE54402 | Up | 0.3118043714 |
| GSE9593 | Down | -0.1454844316 |
| GSE43922 | Down | -0.0261320353 |
| GSE24585 | Up | 0.4865023257 |
| GSE37065 | Down | -0.0461408830 |
| GSE28863_A1 | Up | 0.4448693390 |
| GSE28863_A2 | Up | 0.2566017258 |
| GSE28863_A3 | Down | -0.3337159911 |
| GSE28863_A4 | Up | 0.1297909192 |
| GSE48662 | Up | 0.0011490463 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031372 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-320b | MIMAT0005792 | MIRT036207 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040611 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044023 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044563 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046920 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
