HCSGD entry for SRP54
1. General information
Official gene symbol | SRP54 |
---|---|
Entrez ID | 6729 |
Gene full name | signal recognition particle 54kDa |
Other gene symbols | |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0003924 | GTPase activity | IDA IEA | molecular_function |
GO:0005525 | GTP binding | IDA IEA | molecular_function |
GO:0005634 | Nucleus | IDA | cellular_component |
GO:0005730 | Nucleolus | IDA | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0005786 | Signal recognition particle, endoplasmic reticulum targeting | IDA | cellular_component |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0006184 | GTP catabolic process | IDA | biological_process |
GO:0006412 | Translation | TAS | biological_process |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | IC IEA TAS | biological_process |
GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation | ISS | biological_process |
GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition | ISS | biological_process |
GO:0008144 | Drug binding | IDA | molecular_function |
GO:0008312 | 7S RNA binding | IDA IEA | molecular_function |
GO:0010467 | Gene expression | TAS | biological_process |
GO:0016607 | Nuclear speck | IEA | cellular_component |
GO:0019003 | GDP binding | IDA | molecular_function |
GO:0030942 | Endoplasmic reticulum signal peptide binding | IDA | molecular_function |
GO:0042493 | Response to drug | IDA | biological_process |
GO:0043021 | Ribonucleoprotein complex binding | IDA | molecular_function |
GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
GO:0045047 | Protein targeting to ER | IMP | biological_process |
GO:0048500 | Signal recognition particle | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.0690079100 | 0.8829531325 | 0.5623709997 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.1935132548 |
GSE13712_SHEAR | Up | 0.1257422431 |
GSE13712_STATIC | Up | 0.0966438330 |
GSE19018 | Up | 0.4021881984 |
GSE19899_A1 | Up | 0.4728400315 |
GSE19899_A2 | Up | 0.1070098339 |
PubMed_21979375_A1 | Up | 0.3796734071 |
PubMed_21979375_A2 | Up | 0.1965775233 |
GSE35957 | Down | -0.1960029384 |
GSE36640 | Up | 0.2125769444 |
GSE54402 | Up | 0.2950980489 |
GSE9593 | Down | -0.3508668270 |
GSE43922 | Up | 0.2148067130 |
GSE24585 | Up | 0.2167681868 |
GSE37065 | Up | 0.3030681554 |
GSE28863_A1 | Down | -0.1124629688 |
GSE28863_A2 | Up | 0.2759524170 |
GSE28863_A3 | Down | -0.6902637510 |
GSE28863_A4 | Up | 0.2000099278 |
GSE48662 | Down | -0.3749101827 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-423-5p | MIMAT0004748 | MIRT038146 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord