HCSGD entry for SRP14

1. General information

Official gene symbolSRP14
Entrez ID6727
Gene full namesignal recognition particle 14kDa (homologous Alu RNA binding protein)
Other gene symbolsALURBP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003723RNA bindingTASmolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005786Signal recognition particle, endoplasmic reticulum targetingIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006412TranslationTASbiological_process
GO:0006613Cotranslational protein targeting to membraneTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneIEA TASbiological_process
GO:00083127S RNA bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0030942Endoplasmic reticulum signal peptide bindingIEAmolecular_function
GO:0042493Response to drugIDAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045047Protein targeting to ERIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15360336610.96229645530.78004904501.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2127571715
GSE13712_SHEARDown-0.4007254717
GSE13712_STATICDown-0.1336521269
GSE19018Up0.1438940324
GSE19899_A1Up0.0370684945
GSE19899_A2Up0.1304386463
PubMed_21979375_A1Up0.2920799257
PubMed_21979375_A2Up0.1763324294
GSE35957Up0.1042807771
GSE36640Up0.2307031236
GSE54402Up0.1928768015
GSE9593Up0.1297023219
GSE43922Up0.0601138196
GSE24585Down-0.0226979056
GSE37065Up0.0682458908
GSE28863_A1Up0.4309623500
GSE28863_A2Up0.3198051711
GSE28863_A3Up0.2830872583
GSE28863_A4Up0.0991132520
GSE48662Down-0.1471673443

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028782MicroarrayFunctional MTI (Weak)19088304
hsa-miR-33b-5pMIMAT0003301MIRT039579CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.