HCSGD entry for SRMS


1. General information

Official gene symbolSRMS
Entrez ID6725
Gene full namesrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Other gene symbolsC20orf148 SRM dJ697K14.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004713Protein tyrosine kinase activityIDAmolecular_function
GO:0004715Non-membrane spanning protein tyrosine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0038083Peptidyl-tyrosine autophosphorylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37760760990.90343134760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0775643379
GSE13712_SHEARUp0.0251790656
GSE13712_STATICDown-0.1505814708
GSE19018Up0.1817639407
GSE19899_A1Down-0.0085585998
GSE19899_A2Up0.0175374311
PubMed_21979375_A1Up0.2946741913
PubMed_21979375_A2Up0.0068587508
GSE35957Up0.2085368576
GSE36640Up0.0282752791
GSE54402Down-0.0185532145
GSE9593Up0.0772965864
GSE43922Up0.1003717756
GSE24585Down-0.0298387186
GSE37065Down-0.0171860058
GSE28863_A1Down-0.1303129627
GSE28863_A2Down-0.0558109900
GSE28863_A3Up0.3621506224
GSE28863_A4Up0.1619200501
GSE48662Up0.0771555805

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.