HCSGD entry for SPRR1A
1. General information
| Official gene symbol | SPRR1A |
|---|---|
| Entrez ID | 6698 |
| Gene full name | small proline-rich protein 1A |
| Other gene symbols | SPRK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001533 | Cornified envelope | IDA | cellular_component |
| GO:0005198 | Structural molecule activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0018149 | Peptide cross-linking | IDA | biological_process |
| GO:0030216 | Keratinocyte differentiation | IDA | biological_process |
| GO:0030674 | Protein binding, bridging | IDA | molecular_function |
| GO:0031424 | Keratinization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2734668934 | 0.9642817294 | 0.9702713190 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0252575306 |
| GSE13712_SHEAR | Up | 0.0614685608 |
| GSE13712_STATIC | Up | 0.0370241481 |
| GSE19018 | Up | 0.1341427115 |
| GSE19899_A1 | Up | 0.1328398144 |
| GSE19899_A2 | Down | -0.0345568423 |
| PubMed_21979375_A1 | Up | 0.1549007082 |
| PubMed_21979375_A2 | Down | -0.0572729121 |
| GSE35957 | Up | 0.2755145982 |
| GSE36640 | Down | -0.0469944862 |
| GSE54402 | Up | 0.0108264244 |
| GSE9593 | Up | 0.1770069923 |
| GSE43922 | Up | 0.3081469793 |
| GSE24585 | Up | 0.1321766120 |
| GSE37065 | Up | 0.0051667430 |
| GSE28863_A1 | Down | -0.0623427101 |
| GSE28863_A2 | Up | 0.2187151555 |
| GSE28863_A3 | Up | 0.1889653974 |
| GSE28863_A4 | Up | 0.0535952862 |
| GSE48662 | Up | 0.1785755007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029568 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
