HCSGD entry for SPOCK1

1. General information

Official gene symbolSPOCK1
Entrez ID6695
Gene full namesparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
Other gene symbolsSPOCK TESTICAN TIC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthNASbiological_process
GO:0001764Neuron migrationIEA ISSbiological_process
GO:0004867Serine-type endopeptidase inhibitor activityNASmolecular_function
GO:0004869Cysteine-type endopeptidase inhibitor activityIDAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0007155Cell adhesionNASbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007399Nervous system developmentNASbiological_process
GO:0008191Metalloendopeptidase inhibitor activityIDAmolecular_function
GO:0010812Negative regulation of cell-substrate adhesionIDAbiological_process
GO:0010951Negative regulation of endopeptidase activityIDAbiological_process
GO:0010977Negative regulation of neuron projection developmentIDAbiological_process
GO:0014069Postsynaptic densityNAScellular_component
GO:0016528SarcoplasmIEA ISScellular_component
GO:0021953Central nervous system neuron differentiationIEA ISSbiological_process
GO:0022008NeurogenesisISSbiological_process
GO:0031594Neuromuscular junctionIEA ISScellular_component
GO:0033268Node of RanvierIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22814354700.00474160940.91001246780.1397580067

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.0442495226
GSE13712_SHEARDown-0.3408658043
GSE13712_STATICUp0.0110581997
GSE19018Down-1.9179405259
GSE19899_A1Up0.4622603212
GSE19899_A2Down-1.2960099986
PubMed_21979375_A1Down-2.0622353978
PubMed_21979375_A2Down-0.5954131557
GSE35957Down-0.3227046691
GSE36640Down-1.8691789750
GSE54402Down-0.4562540775
GSE9593Up1.2385061944
GSE43922Up0.2203638735
GSE24585Up1.4685454630
GSE37065Down-0.1666094212
GSE28863_A1Down-0.0890887164
GSE28863_A2Up0.4316225667
GSE28863_A3Down-0.0138540750
GSE28863_A4Up0.0921849877
GSE48662Down-0.4612029694

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.