HCSGD entry for SPP2

1. General information

Official gene symbolSPP2
Entrez ID6694
Gene full namesecreted phosphoprotein 2, 24kDa
Other gene symbolsSPP-24 SPP24
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentTASbiological_process
GO:0004866Endopeptidase inhibitor activityTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006461Protein complex assemblyIEAbiological_process
GO:0010466Negative regulation of peptidase activityTASbiological_process
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0046849Bone remodelingIEAbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0052547Regulation of peptidase activityTASbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87314418150.64848153190.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0145435763
GSE13712_SHEARDown-0.3362766026
GSE13712_STATICDown-0.1763968366
GSE19018Down-0.0111536152
GSE19899_A1Up0.1606325818
GSE19899_A2Up0.0088088123
PubMed_21979375_A1Up0.0317998616
PubMed_21979375_A2Up0.1755389510
GSE35957Down-0.1430203336
GSE36640Up0.0743396862
GSE54402Up0.1109371491
GSE9593Down-0.0598785436
GSE43922Up0.0180951815
GSE24585Up0.0764552101
GSE37065Down-0.1108112792
GSE28863_A1Up0.0012674462
GSE28863_A2Up0.0658850040
GSE28863_A3Down-0.0159039490
GSE28863_A4Down-0.0061139268
GSE48662Down-0.0478202024

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.