HCSGD entry for SPN

1. General information

Official gene symbolSPN
Entrez ID6693
Gene full namesialophorin
Other gene symbolsCD43 GALGP GPL115 LSN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001562Response to protozoanIEAbiological_process
GO:0001808Negative regulation of type IV hypersensitivityIEAbiological_process
GO:0001931UropodIEAcellular_component
GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005604Basement membraneIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006935ChemotaxisTASbiological_process
GO:0006955Immune responseTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007162Negative regulation of cell adhesionIEAbiological_process
GO:0007163Establishment or maintenance of cell polarityTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007166Cell surface receptor signaling pathwayIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0031295T cell costimulationIEAbiological_process
GO:0042102Positive regulation of T cell proliferationIEAbiological_process
GO:0042130Negative regulation of T cell proliferationIEAbiological_process
GO:0042535Positive regulation of tumor necrosis factor biosynthetic processIDA IEAbiological_process
GO:0042742Defense response to bacteriumIDA IEAbiological_process
GO:0045060Negative thymic T cell selectionIEAbiological_process
GO:0050688Regulation of defense response to virusIEAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
GO:0097190Apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88057903960.27597364460.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0814204497
GSE13712_SHEARDown-0.0384800547
GSE13712_STATICUp0.0634930035
GSE19018Up0.0486052959
GSE19899_A1Up0.0854987592
GSE19899_A2Down-0.0414419072
PubMed_21979375_A1Down-0.3096061939
PubMed_21979375_A2Down-0.2033833237
GSE35957Up0.1196608510
GSE36640Down-0.0491098075
GSE54402Down-0.0058120810
GSE9593Down-0.0920514037
GSE43922Up0.0138031757
GSE24585Up0.0539415011
GSE37065Up0.0801569338
GSE28863_A1Down-0.3548364286
GSE28863_A2Down-0.5478321032
GSE28863_A3Up0.4191298949
GSE28863_A4Down-0.1019140727
GSE48662Up0.1099036668

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7e-5pMIMAT0000066MIRT051630CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052328CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.