HCSGD entry for SPINT1
1. General information
| Official gene symbol | SPINT1 |
|---|---|
| Entrez ID | 6692 |
| Gene full name | serine peptidase inhibitor, Kunitz type 1 |
| Other gene symbols | HAI HAI1 MANSC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0030198 | Extracellular matrix organization | IEA | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
| GO:0060670 | Branching involved in labyrinthine layer morphogenesis | IEA | biological_process |
| GO:0060674 | Placenta blood vessel development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2185868318 | 0.8745622241 | 0.8992535167 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1491313543 |
| GSE13712_SHEAR | Down | -0.0001650972 |
| GSE13712_STATIC | Up | 0.4184251198 |
| GSE19018 | Up | 0.1894302188 |
| GSE19899_A1 | Up | 0.0415838101 |
| GSE19899_A2 | Up | 0.0121098553 |
| PubMed_21979375_A1 | Down | -0.0341192782 |
| PubMed_21979375_A2 | Up | 0.2149704829 |
| GSE35957 | Up | 0.0667293127 |
| GSE36640 | Down | -0.1216190011 |
| GSE54402 | Up | 0.0340535219 |
| GSE9593 | Down | -0.0793214731 |
| GSE43922 | Up | 0.1549117885 |
| GSE24585 | Up | 0.2018574338 |
| GSE37065 | Up | 0.2301805540 |
| GSE28863_A1 | Down | -0.2079507950 |
| GSE28863_A2 | Down | -0.1107933282 |
| GSE28863_A3 | Up | 0.4684072414 |
| GSE28863_A4 | Up | 0.1487081424 |
| GSE48662 | Up | 0.0215758824 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
