HCSGD entry for BNIP3L
1. General information
| Official gene symbol | BNIP3L |
|---|---|
| Entrez ID | 665 |
| Gene full name | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| Other gene symbols | BNIP3a NIX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005521 | Lamin binding | IDA IPI | molecular_function |
| GO:0005635 | Nuclear envelope | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005740 | Mitochondrial envelope | IEA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IMP | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0031224 | Intrinsic component of membrane | TAS | cellular_component |
| GO:0035694 | Mitochondrial protein catabolic process | IMP | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IDA IEA | molecular_function |
| GO:0043065 | Positive regulation of apoptotic process | IDA IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
| GO:0051607 | Defense response to virus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0085034877 | 0.6528309905 | 0.2370178270 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2747873969 |
| GSE13712_SHEAR | Down | -0.3755032266 |
| GSE13712_STATIC | Down | -0.6149294253 |
| GSE19018 | Up | 1.7734138661 |
| GSE19899_A1 | Up | 0.3757500487 |
| GSE19899_A2 | Up | 1.1357666752 |
| PubMed_21979375_A1 | Up | 0.9404970461 |
| PubMed_21979375_A2 | Up | 1.0213661225 |
| GSE35957 | Up | 0.0941313017 |
| GSE36640 | Down | -0.3043485188 |
| GSE54402 | Up | 0.2594807341 |
| GSE9593 | Up | 0.2783960368 |
| GSE43922 | Up | 0.0675217662 |
| GSE24585 | Up | 0.8295510320 |
| GSE37065 | Up | 0.1068790159 |
| GSE28863_A1 | Up | 0.1571728445 |
| GSE28863_A2 | Up | 0.6939735641 |
| GSE28863_A3 | Up | 0.1184670767 |
| GSE28863_A4 | Down | -0.5509088030 |
| GSE48662 | Up | 0.1271456019 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT003359 | Reporter assay;Western blot;qRT-PCR;Microarray | Functional MTI | 20018759 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052099 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052472 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | NA | hsa-miR-221 | {Western blot} | {overexpression by miRNA precursor transfection} | 20018759 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
