HCSGD entry for SOD3
1. General information
| Official gene symbol | SOD3 |
|---|---|
| Entrez ID | 6649 |
| Gene full name | superoxide dismutase 3, extracellular |
| Other gene symbols | EC-SOD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0004784 | Superoxide dismutase activity | IBA IEA | molecular_function |
| GO:0005507 | Copper ion binding | IBA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IDA IEA | cellular_component |
| GO:0005634 | Nucleus | IBA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IBA | cellular_component |
| GO:0005802 | Trans-Golgi network | IEA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006801 | Superoxide metabolic process | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IBA IEA | molecular_function |
| GO:0019430 | Removal of superoxide radicals | IBA | biological_process |
| GO:0031012 | Extracellular matrix | IDA IEA | cellular_component |
| GO:0046688 | Response to copper ion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3025769728 | 0.2034057293 | 0.9999902473 | 0.8735262196 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0870508246 |
| GSE13712_SHEAR | Down | -0.0433712620 |
| GSE13712_STATIC | Up | 0.0230307117 |
| GSE19018 | Up | 0.0518217870 |
| GSE19899_A1 | Down | -0.2731353055 |
| GSE19899_A2 | Up | 0.0275114480 |
| PubMed_21979375_A1 | Down | -0.5428832699 |
| PubMed_21979375_A2 | Down | -0.3195964495 |
| GSE35957 | Up | 0.3752484563 |
| GSE36640 | Up | 0.6770949284 |
| GSE54402 | Down | -0.7195489892 |
| GSE9593 | Down | -0.4274070547 |
| GSE43922 | Up | 0.0266622797 |
| GSE24585 | Up | 0.0973080442 |
| GSE37065 | Up | 0.0464561882 |
| GSE28863_A1 | Up | 0.2299324957 |
| GSE28863_A2 | Up | 0.7587918802 |
| GSE28863_A3 | Up | 0.0711151477 |
| GSE28863_A4 | Down | -0.2813869647 |
| GSE48662 | Up | 0.3335041717 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT006997 | Luciferase reporter assay | Functional MTI | 22836756 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
