HCSGD entry for SNX2
1. General information
| Official gene symbol | SNX2 |
|---|---|
| Entrez ID | 6643 |
| Gene full name | sorting nexin 2 |
| Other gene symbols | TRG-9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006897 | Endocytosis | TAS | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0010008 | Endosome membrane | IDA | cellular_component |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9131890202 | 0.1623519585 | 0.9999902473 | 0.7783726594 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1781137953 |
| GSE13712_SHEAR | Down | -0.1658020927 |
| GSE13712_STATIC | Up | 0.0149553537 |
| GSE19018 | Up | 0.1663564358 |
| GSE19899_A1 | Down | -0.2756399735 |
| GSE19899_A2 | Down | -0.1396257363 |
| PubMed_21979375_A1 | Down | -0.2146481468 |
| PubMed_21979375_A2 | Down | -0.1567572793 |
| GSE35957 | Up | 0.2055071741 |
| GSE36640 | Down | -0.0116876688 |
| GSE54402 | Down | -0.2592006525 |
| GSE9593 | Up | 0.1276041769 |
| GSE43922 | Down | -0.3404612453 |
| GSE24585 | Up | 0.0813168660 |
| GSE37065 | Up | 0.1370135478 |
| GSE28863_A1 | Down | -0.0505753539 |
| GSE28863_A2 | Up | 0.3424093210 |
| GSE28863_A3 | Down | -0.4873548988 |
| GSE28863_A4 | Down | -0.2831013600 |
| GSE48662 | Down | -0.3682743777 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029279 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047884 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052540 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
