HCSGD entry for SMPD2
1. General information
| Official gene symbol | SMPD2 |
|---|---|
| Entrez ID | 6610 |
| Gene full name | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| Other gene symbols | ISC1 NSMASE NSMASE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004767 | Sphingomyelin phosphodiesterase activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005901 | Caveola | IEA | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006684 | Sphingomyelin metabolic process | TAS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0009612 | Response to mechanical stimulus | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4229603511 | 0.5131084647 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1091505754 |
| GSE13712_SHEAR | Up | 0.2479506887 |
| GSE13712_STATIC | Down | -0.0455803982 |
| GSE19018 | Up | 0.2010968747 |
| GSE19899_A1 | Down | -0.1328567037 |
| GSE19899_A2 | Up | 0.1786799453 |
| PubMed_21979375_A1 | Up | 0.5568100744 |
| PubMed_21979375_A2 | Up | 0.4409694128 |
| GSE35957 | Down | -0.2447349078 |
| GSE36640 | Down | -0.0290966612 |
| GSE54402 | Up | 0.0939303698 |
| GSE9593 | Down | -0.0576734090 |
| GSE43922 | Down | -0.0595923542 |
| GSE24585 | Down | -0.5255868591 |
| GSE37065 | Down | -0.0210320136 |
| GSE28863_A1 | Up | 0.2713155510 |
| GSE28863_A2 | Up | 0.0408198645 |
| GSE28863_A3 | Down | -0.3206057352 |
| GSE28863_A4 | Down | -0.0949106141 |
| GSE48662 | Up | 0.0473475027 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
