HCSGD entry for SMARCC2
1. General information
| Official gene symbol | SMARCC2 |
|---|---|
| Entrez ID | 6601 |
| Gene full name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
| Other gene symbols | BAF170 CRACC2 Rsc8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006337 | Nucleosome disassembly | IDA | biological_process |
| GO:0006338 | Chromatin remodeling | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0016514 | SWI/SNF complex | IDA | cellular_component |
| GO:0017053 | Transcriptional repressor complex | IPI | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0071564 | NpBAF complex | IEA ISS | cellular_component |
| GO:0071565 | NBAF complex | IEA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6738542837 | 0.2641700733 | 0.9999902473 | 0.9862085779 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0404286455 |
| GSE13712_SHEAR | Down | -0.2032373550 |
| GSE13712_STATIC | Down | -0.1290553261 |
| GSE19018 | Down | -0.0066144271 |
| GSE19899_A1 | Down | -0.1914480905 |
| GSE19899_A2 | Down | -0.0488821147 |
| PubMed_21979375_A1 | Down | -0.9292824749 |
| PubMed_21979375_A2 | Up | 0.0444903164 |
| GSE35957 | Down | -0.0414225160 |
| GSE36640 | Down | -0.0316621601 |
| GSE54402 | Down | -0.1439661599 |
| GSE9593 | Down | -0.1692857031 |
| GSE43922 | Down | -0.5219239869 |
| GSE24585 | Up | 0.1326484173 |
| GSE37065 | Down | -0.0881657987 |
| GSE28863_A1 | Up | 0.3653884722 |
| GSE28863_A2 | Up | 0.2629709390 |
| GSE28863_A3 | Up | 0.0991034537 |
| GSE28863_A4 | Up | 0.0867880192 |
| GSE48662 | Up | 0.3666337413 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025434 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040220 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040733 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044683 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045221 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
