HCSGD entry for SMARCC1
1. General information
| Official gene symbol | SMARCC1 |
|---|---|
| Entrez ID | 6599 |
| Gene full name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 |
| Other gene symbols | BAF155 CRACC1 Rsc8 SRG3 SWI3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001741 | XY body | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006337 | Nucleosome disassembly | IDA | biological_process |
| GO:0006338 | Chromatin remodeling | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | IEA | biological_process |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0016514 | SWI/SNF complex | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0071564 | NpBAF complex | IEA ISS | cellular_component |
| GO:0071565 | NBAF complex | IEA ISS | cellular_component |
| GO:0071778 | WINAC complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2806089776 | 0.2845545838 | 0.9782851264 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0748035927 |
| GSE13712_SHEAR | Up | 0.2513631918 |
| GSE13712_STATIC | Down | -0.0732227469 |
| GSE19018 | Down | -0.3321185177 |
| GSE19899_A1 | Up | 0.2192139984 |
| GSE19899_A2 | Down | -0.0616689874 |
| PubMed_21979375_A1 | Up | 0.0965462547 |
| PubMed_21979375_A2 | Up | 0.3403553231 |
| GSE35957 | Down | -0.1413840500 |
| GSE36640 | Down | -1.0101019879 |
| GSE54402 | Up | 0.4398061568 |
| GSE9593 | Down | -0.0865246991 |
| GSE43922 | Up | 0.0602278662 |
| GSE24585 | Down | -0.1631903367 |
| GSE37065 | Down | -0.2380163460 |
| GSE28863_A1 | Up | 0.4306864292 |
| GSE28863_A2 | Up | 0.4303449709 |
| GSE28863_A3 | Up | 0.1998878890 |
| GSE28863_A4 | Down | -0.2703799217 |
| GSE48662 | Down | -0.3189544088 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023740 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025422 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027600 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032311 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048376 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051378 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051857 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
