HCSGD entry for PHACTR4
1. General information
| Official gene symbol | PHACTR4 |
|---|---|
| Entrez ID | 65979 |
| Gene full name | phosphatase and actin regulator 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001755 | Neural crest cell migration | ISS | biological_process |
| GO:0001843 | Neural tube closure | ISS | biological_process |
| GO:0003779 | Actin binding | ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007266 | Rho protein signal transduction | ISS | biological_process |
| GO:0008157 | Protein phosphatase 1 binding | ISS | molecular_function |
| GO:0030027 | Lamellipodium | ISS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | ISS | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | ISS | biological_process |
| GO:0048484 | Enteric nervous system development | ISS | biological_process |
| GO:0051726 | Regulation of cell cycle | ISS | biological_process |
| GO:0061386 | Closure of optic fissure | ISS | biological_process |
| GO:0071862 | Protein phosphatase type 1 activator activity | ISS | molecular_function |
| GO:2001045 | Negative regulation of integrin-mediated signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9703428973 | 0.0513851069 | 0.9999902473 | 0.4262345936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1239924549 |
| GSE13712_SHEAR | Down | -0.1438132674 |
| GSE13712_STATIC | Down | -0.1029645307 |
| GSE19018 | Down | -0.1605224242 |
| GSE19899_A1 | Down | -0.8427506314 |
| GSE19899_A2 | Down | -0.2122492413 |
| PubMed_21979375_A1 | Down | -0.5320668028 |
| PubMed_21979375_A2 | Down | -0.0187465017 |
| GSE35957 | Down | -0.7938591013 |
| GSE36640 | Down | -0.2975708046 |
| GSE54402 | Down | -0.1644110777 |
| GSE9593 | Down | -0.2989755710 |
| GSE43922 | Down | -0.2311352889 |
| GSE24585 | Up | 0.3808975670 |
| GSE37065 | Up | 0.3147539526 |
| GSE28863_A1 | Down | -0.0153719602 |
| GSE28863_A2 | Down | -0.0385232939 |
| GSE28863_A3 | Down | -0.0548044577 |
| GSE28863_A4 | Down | -0.1799736624 |
| GSE48662 | Down | -0.0216246295 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-361-5p | MIMAT0000703 | MIRT020099 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027757 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036983 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041759 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049161 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
