HCSGD entry for PLEKHA3
1. General information
| Official gene symbol | PLEKHA3 |
|---|---|
| Entrez ID | 65977 |
| Gene full name | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 |
| Other gene symbols | FAPP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005543 | Phospholipid binding | IDA | molecular_function |
| GO:0005545 | 1-phosphatidylinositol binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1699624102 | 0.5086555868 | 0.8116075109 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2889561222 |
| GSE13712_SHEAR | Down | -0.1987561118 |
| GSE13712_STATIC | Down | -0.0768473143 |
| GSE19018 | Up | 0.0835577483 |
| GSE19899_A1 | Up | 0.1982896008 |
| GSE19899_A2 | Up | 0.5136879042 |
| PubMed_21979375_A1 | Down | -0.1387307029 |
| PubMed_21979375_A2 | Up | 0.0306342303 |
| GSE35957 | Up | 0.2363430493 |
| GSE36640 | Up | 0.4341031440 |
| GSE54402 | Up | 0.3283281103 |
| GSE9593 | Up | 0.4096123876 |
| GSE43922 | Up | 0.1430600170 |
| GSE24585 | Down | -0.6937302376 |
| GSE37065 | Up | 0.2255446913 |
| GSE28863_A1 | Down | -0.0573989414 |
| GSE28863_A2 | Up | 0.1952330935 |
| GSE28863_A3 | Down | -0.6326069690 |
| GSE28863_A4 | Down | -0.2968364347 |
| GSE48662 | Up | 0.0740782024 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019877 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021709 | Microarray | Functional MTI (Weak) | 21396852 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
