HCSGD entry for SLC22A3
1. General information
| Official gene symbol | SLC22A3 |
|---|---|
| Entrez ID | 6581 |
| Gene full name | solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
| Other gene symbols | EMT EMTH OCT3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005329 | Dopamine transmembrane transporter activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006855 | Drug transmembrane transport | TAS | biological_process |
| GO:0015075 | Ion transmembrane transporter activity | IEA | molecular_function |
| GO:0015101 | Organic cation transmembrane transporter activity | IDA | molecular_function |
| GO:0015651 | Quaternary ammonium group transmembrane transporter activity | IDA | molecular_function |
| GO:0015695 | Organic cation transport | IDA | biological_process |
| GO:0015697 | Quaternary ammonium group transport | IDA | biological_process |
| GO:0015872 | Dopamine transport | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019534 | Toxin transporter activity | IEA | molecular_function |
| GO:0032098 | Regulation of appetite | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051615 | Histamine uptake | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4417546028 | 0.1771064929 | 0.9999902473 | 0.8141841710 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4171707175 |
| GSE13712_SHEAR | Up | 0.3069203487 |
| GSE13712_STATIC | Up | 0.0267093981 |
| GSE19018 | Down | -0.0314688429 |
| GSE19899_A1 | Down | -0.0568616245 |
| GSE19899_A2 | Down | -0.0208593475 |
| PubMed_21979375_A1 | Up | 0.0039191545 |
| PubMed_21979375_A2 | Up | 0.0473115405 |
| GSE35957 | Up | 0.7304889577 |
| GSE36640 | Up | 0.1022429807 |
| GSE54402 | Up | 0.1652302580 |
| GSE9593 | Down | -1.2592052357 |
| GSE43922 | Up | 0.0478170230 |
| GSE24585 | Down | -0.1563463479 |
| GSE37065 | Down | -0.1691225952 |
| GSE28863_A1 | Down | -0.0130788469 |
| GSE28863_A2 | Up | 0.1295294036 |
| GSE28863_A3 | Up | 0.2043947784 |
| GSE28863_A4 | Up | 0.0450057423 |
| GSE48662 | Down | -0.2922036191 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019444 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021441 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022967 | Microarray | Functional MTI (Weak) | 18668037 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
