HCSGD entry for SLC22A1

1. General information

Official gene symbolSLC22A1
Entrez ID6580
Gene full namesolute carrier family 22 (organic cation transporter), member 1
Other gene symbolsHOCT1 OCT1 oct1_cds
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005277Acetylcholine transmembrane transporter activityIEAmolecular_function
GO:0005329Dopamine transmembrane transporter activityIEAmolecular_function
GO:0005333Norepinephrine transmembrane transporter activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEA TAScellular_component
GO:0006855Drug transmembrane transportIEA TASbiological_process
GO:0008513Secondary active organic cation transmembrane transporter activityIEAmolecular_function
GO:0010248Establishment or maintenance of transmembrane electrochemical gradientIEAbiological_process
GO:0015101Organic cation transmembrane transporter activityTASmolecular_function
GO:0015651Quaternary ammonium group transmembrane transporter activityIEAmolecular_function
GO:0015695Organic cation transportTASbiological_process
GO:0015872Dopamine transportIEAbiological_process
GO:0015874Norepinephrine transportIEAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048241Epinephrine transportIEAbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04974003270.96503401850.48894641521.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0076763878
GSE13712_SHEARUp0.1021167090
GSE13712_STATICUp0.1920490268
GSE19018Up0.0464359293
GSE19899_A1Down-0.0005978360
GSE19899_A2Up0.4793003749
PubMed_21979375_A1Up1.5616982862
PubMed_21979375_A2Up0.3240309804
GSE35957Up0.0492974839
GSE36640Up0.1924714163
GSE54402Up0.1272240501
GSE9593Up0.2833679424
GSE43922Up0.7136774315
GSE24585Down-0.3156672111
GSE37065Up0.2924857355
GSE28863_A1Down-0.1325715897
GSE28863_A2Up0.0997305443
GSE28863_A3Up0.1835561099
GSE28863_A4Up0.1441009976
GSE48662Up0.0631712342

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.