HCSGD entry for SLC6A8

1. General information

Official gene symbolSLC6A8
Entrez ID6535
Gene full namesolute carrier family 6 (neurotransmitter transporter, creatine), member 8
Other gene symbolsCRT CRTR CT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportNAS TASbiological_process
GO:0003674Molecular_functionNDmolecular_function
GO:0005308Creatine transmembrane transporter activityNASmolecular_function
GO:0005309Creatine:sodium symporter activityIEAmolecular_function
GO:0005328Neurotransmitter:sodium symporter activityIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006600Creatine metabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0008150Biological_processNDbiological_process
GO:0015220Choline transmembrane transporter activityIEAmolecular_function
GO:0015881Creatine transportNASbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0034220Ion transmembrane transportNAS TASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051181Cofactor transportNAS TASbiological_process
GO:0055085Transmembrane transportNAS TASbiological_process
GO:1902598Creatine transmembrane transportNAS TASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01085001710.83756845860.26362348071.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2954586201
GSE13712_SHEARDown-0.4835248025
GSE13712_STATICUp0.0296396034
GSE19018Up0.2431940571
GSE19899_A1Up0.3427712729
GSE19899_A2Up1.1073129122
PubMed_21979375_A1Up2.1056283001
PubMed_21979375_A2Up2.9874040584
GSE35957Up0.0987867959
GSE36640Up0.5478803683
GSE54402Up0.1866219507
GSE9593Up0.1774844993
GSE43922Up0.2429687073
GSE24585Down-0.3779252692
GSE37065Down-0.0429562367
GSE28863_A1Up0.0128333561
GSE28863_A2Up0.0076096382
GSE28863_A3Up0.1926754233
GSE28863_A4Up0.0036544912
GSE48662Up0.4612460240

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT036805CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041648CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044490CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048259CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049670CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.