HCSGD entry for SRGAP2C
1. General information
| Official gene symbol | SRGAP2C |
|---|---|
| Entrez ID | 653464 |
| Gene full name | SLIT-ROBO Rho GTPase activating protein 2C |
| Other gene symbols | SRGAP2P1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0021816 | Extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051490 | Negative regulation of filopodium assembly | IDA | biological_process |
| GO:0061000 | Negative regulation of dendritic spine development | IDA | biological_process |
| GO:2001224 | Positive regulation of neuron migration | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3686171688 | 0.0663136469 | 0.9999902473 | 0.4855191933 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3136526624 |
| GSE13712_SHEAR | Up | 0.1658709353 |
| GSE13712_STATIC | Down | -0.2563745808 |
| GSE19018 | Up | 0.5442374322 |
| GSE19899_A1 | Down | -0.1243972223 |
| GSE19899_A2 | Down | -1.1196314005 |
| PubMed_21979375_A1 | Down | -1.4257472138 |
| PubMed_21979375_A2 | Down | -0.1395848055 |
| GSE35957 | Down | -0.3918968408 |
| GSE36640 | Down | -0.5816809180 |
| GSE54402 | Down | -0.2001737853 |
| GSE9593 | Up | 0.1687319510 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.7505112031 |
| GSE28863_A2 | Up | 0.8889639231 |
| GSE28863_A3 | Down | -0.0703738482 |
| GSE28863_A4 | Down | -0.0157564236 |
| GSE48662 | Down | -0.0940191745 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018505 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
