HCSGD entry for SLC6A6
1. General information
| Official gene symbol | SLC6A6 |
|---|---|
| Entrez ID | 6533 |
| Gene full name | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
| Other gene symbols | TAUT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005328 | Neurotransmitter:sodium symporter activity | IEA | molecular_function |
| GO:0005369 | Taurine:sodium symporter activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0015672 | Monovalent inorganic cation transport | TAS | biological_process |
| GO:0015734 | Taurine transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0030001 | Metal ion transport | TAS | biological_process |
| GO:0030977 | Taurine binding | IEA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0788793967 | 0.6716706432 | 0.5911687358 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3716518534 |
| GSE13712_SHEAR | Down | -0.3364583414 |
| GSE13712_STATIC | Up | 0.1136814888 |
| GSE19018 | Up | 0.2132945594 |
| GSE19899_A1 | Up | 0.2790594056 |
| GSE19899_A2 | Up | 0.3582253336 |
| PubMed_21979375_A1 | Down | -0.2857897817 |
| PubMed_21979375_A2 | Up | 0.3783142032 |
| GSE35957 | Down | -0.5111547724 |
| GSE36640 | Up | 0.3013634931 |
| GSE54402 | Up | 0.3477089957 |
| GSE9593 | Up | 0.5426224583 |
| GSE43922 | Down | -0.1166817092 |
| GSE24585 | Up | 0.0965320902 |
| GSE37065 | Up | 0.3033921803 |
| GSE28863_A1 | Up | 0.3098008268 |
| GSE28863_A2 | Up | 0.2509147853 |
| GSE28863_A3 | Down | -0.1195679612 |
| GSE28863_A4 | Down | -0.1999257942 |
| GSE48662 | Up | 0.6167622936 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019132 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-375 | MIMAT0000728 | MIRT020030 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038054 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045237 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050435 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
