HCSGD entry for BMP5

1. General information

Official gene symbolBMP5
Entrez ID653
Gene full namebone morphogenetic protein 5
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentNASbiological_process
GO:0001503OssificationIEAbiological_process
GO:0003323Type B pancreatic cell developmentIDAbiological_process
GO:0005125Cytokine activityIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005576Extracellular regionIEAcellular_component
GO:0005615Extracellular spaceISScellular_component
GO:0007389Pattern specification processIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0010719Negative regulation of epithelial to mesenchymal transitionNASbiological_process
GO:0010862Positive regulation of pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:0010894Negative regulation of steroid biosynthetic processIDAbiological_process
GO:0030539Male genitalia developmentIEAbiological_process
GO:0031988Membrane-bounded vesicleISScellular_component
GO:0032348Negative regulation of aldosterone biosynthetic processIDAbiological_process
GO:0040007GrowthIEAbiological_process
GO:0043569Negative regulation of insulin-like growth factor receptor signaling pathwayIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIDAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0070700BMP receptor bindingIPImolecular_function
GO:0071676Negative regulation of mononuclear cell migrationNASbiological_process
GO:1900006Positive regulation of dendrite developmentIDAbiological_process
GO:1902042Negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsNASbiological_process
GO:2000065Negative regulation of cortisol biosynthetic processIDAbiological_process
GO:2000105Positive regulation of DNA-dependent DNA replicationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93206075380.12891150030.99999024730.6913365118

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0665274395
GSE13712_SHEARDown-0.1600289764
GSE13712_STATICDown-0.0955399378
GSE19018Down-0.0352510224
GSE19899_A1Down-0.0915620932
GSE19899_A2Down-0.2915295822
PubMed_21979375_A1Up0.0046364422
PubMed_21979375_A2Down-0.1207450184
GSE35957Up0.1454365007
GSE36640Down-0.2851237000
GSE54402Down-1.0687234610
GSE9593Down-1.5260411437
GSE43922Up0.0050151692
GSE24585Up0.4360816300
GSE37065Up0.0664372179
GSE28863_A1Down-0.0325515770
GSE28863_A2Down-0.0113195487
GSE28863_A3Up0.0760205873
GSE28863_A4Down-0.0261421499
GSE48662Down-0.0458317716

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.