HCSGD entry for PYCRL
1. General information
| Official gene symbol | PYCRL |
|---|---|
| Entrez ID | 65263 |
| Gene full name | pyrroline-5-carboxylate reductase-like |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004735 | Pyrroline-5-carboxylate reductase activity | IEA | molecular_function |
| GO:0006561 | Proline biosynthetic process | IEA | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0055129 | L-proline biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7932178489 | 0.2798396793 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0207389010 |
| GSE13712_SHEAR | Up | 0.3318027897 |
| GSE13712_STATIC | Down | -0.1553799509 |
| GSE19018 | Down | -0.2511734447 |
| GSE19899_A1 | Down | -0.0521076349 |
| GSE19899_A2 | Up | 0.1649256459 |
| PubMed_21979375_A1 | Up | 0.5091057473 |
| PubMed_21979375_A2 | Up | 0.0855022663 |
| GSE35957 | Down | -0.1850909645 |
| GSE36640 | Down | -0.2704516279 |
| GSE54402 | Up | 0.2132181579 |
| GSE9593 | Down | -0.0868049929 |
| GSE43922 | Up | 0.0528830630 |
| GSE24585 | Down | -0.4235016082 |
| GSE37065 | Down | -0.3046498301 |
| GSE28863_A1 | Down | -0.1381190738 |
| GSE28863_A2 | Down | -0.1018093705 |
| GSE28863_A3 | Up | 0.0564628604 |
| GSE28863_A4 | Down | -0.0416947463 |
| GSE48662 | Down | -0.0176622478 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032383 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
