HCSGD entry for SLC3A1

1. General information

Official gene symbolSLC3A1
Entrez ID6519
Gene full namesolute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
Other gene symbolsATR1 CSNU1 D2H NBAT RBAT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportTASbiological_process
GO:0003824Catalytic activityIEAmolecular_function
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005774Vacuolar membraneIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0006520Cellular amino acid metabolic processTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006865Amino acid transportIEA TASbiological_process
GO:0015171Amino acid transmembrane transporter activityTASmolecular_function
GO:0015174Basic amino acid transmembrane transporter activityTASmolecular_function
GO:0015184L-cystine transmembrane transporter activityTASmolecular_function
GO:0015802Basic amino acid transportTASbiological_process
GO:0015811L-cystine transportTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043169Cation bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:1902475L-alpha-amino acid transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65504937120.62912411760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0459442892
GSE13712_SHEARDown-0.0239201360
GSE13712_STATICDown-0.2064451912
GSE19018Up0.2546079602
GSE19899_A1Up0.0640740629
GSE19899_A2Down-0.1430598333
PubMed_21979375_A1Down-0.5576592873
PubMed_21979375_A2Down-0.1947560459
GSE35957Up0.2134166366
GSE36640Up0.5446873382
GSE54402Down-0.1224824661
GSE9593Up0.2784275849
GSE43922Up0.0802033054
GSE24585Up0.1903010973
GSE37065Down-0.0621460328
GSE28863_A1Down-0.1022938840
GSE28863_A2Down-0.1602157154
GSE28863_A3Up0.0578301833
GSE28863_A4Down-0.1160090468
GSE48662Up0.0354738708

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-CystineDB00138 NUTR00023

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.