HCSGD entry for SLC2A1
1. General information
| Official gene symbol | SLC2A1 |
|---|---|
| Entrez ID | 6513 |
| Gene full name | solute carrier family 2 (facilitated glucose transporter), member 1 |
| Other gene symbols | DYT17 DYT18 DYT9 EIG12 GLUT GLUT1 GLUT1DS HTLVR PED |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001939 | Female pronucleus | IEA | cellular_component |
| GO:0005355 | Glucose transmembrane transporter activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005901 | Caveola | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006461 | Protein complex assembly | IDA | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006970 | Response to osmotic stress | IEA | biological_process |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0015758 | Glucose transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0019852 | L-ascorbic acid metabolic process | TAS | biological_process |
| GO:0019900 | Kinase binding | IEA | molecular_function |
| GO:0022857 | Transmembrane transporter activity | IEA | molecular_function |
| GO:0022891 | Substrate-specific transmembrane transporter activity | IEA | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0030864 | Cortical actin cytoskeleton | IDA | cellular_component |
| GO:0033300 | Dehydroascorbic acid transporter activity | IEA | molecular_function |
| GO:0034219 | Carbohydrate transmembrane transport | TAS | biological_process |
| GO:0035428 | Hexose transmembrane transport | TAS | biological_process |
| GO:0042149 | Cellular response to glucose starvation | IEA | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042910 | Xenobiotic transporter activity | IEA | molecular_function |
| GO:0043621 | Protein self-association | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
| GO:0055056 | D-glucose transmembrane transporter activity | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3167961172 | 0.0102578283 | 0.9999902473 | 0.2002939911 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1724977002 |
| GSE13712_SHEAR | Down | -0.0268191391 |
| GSE13712_STATIC | Down | -0.1738110210 |
| GSE19018 | Up | 1.5977974158 |
| GSE19899_A1 | Down | -1.5038914213 |
| GSE19899_A2 | Down | -0.4506795603 |
| PubMed_21979375_A1 | Down | -0.5414235122 |
| PubMed_21979375_A2 | Down | -0.4790798798 |
| GSE35957 | Down | -0.5227187825 |
| GSE36640 | Down | -0.2654206730 |
| GSE54402 | Down | -0.7100495826 |
| GSE9593 | Up | 0.1383678141 |
| GSE43922 | Down | -0.7175882755 |
| GSE24585 | Up | 0.2647959559 |
| GSE37065 | Up | 0.1558496214 |
| GSE28863_A1 | Down | -0.1740206235 |
| GSE28863_A2 | Up | 0.7751990048 |
| GSE28863_A3 | Down | -0.0760777579 |
| GSE28863_A4 | Down | -0.2097265743 |
| GSE48662 | Up | 0.4857081417 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1262 | MIMAT0005914 | MIRT035848 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041808 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042866 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044855 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045432 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
