HCSGD entry for INTS3
1. General information
| Official gene symbol | INTS3 |
|---|---|
| Entrez ID | 65123 |
| Gene full name | integrator complex subunit 3 |
| Other gene symbols | C1orf193 C1orf60 INT3 SOSS-A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006281 | DNA repair | IMP | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IMP | biological_process |
| GO:0007093 | Mitotic cell cycle checkpoint | IMP | biological_process |
| GO:0010212 | Response to ionizing radiation | IMP | biological_process |
| GO:0016180 | SnRNA processing | IDA | biological_process |
| GO:0032039 | Integrator complex | IDA | cellular_component |
| GO:0070876 | SOSS complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9579368679 | 0.0871544470 | 0.9999902473 | 0.5601635986 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0222089760 |
| GSE13712_SHEAR | Down | -0.0718767412 |
| GSE13712_STATIC | Down | -0.0659675189 |
| GSE19018 | Up | 0.0394231960 |
| GSE19899_A1 | Down | -0.1264372452 |
| GSE19899_A2 | Down | -0.1085269297 |
| PubMed_21979375_A1 | Down | -1.0508682982 |
| PubMed_21979375_A2 | Up | 0.1229420097 |
| GSE35957 | Down | -0.3364927373 |
| GSE36640 | Up | 0.0417597966 |
| GSE54402 | Down | -0.3107586678 |
| GSE9593 | Down | -0.0165814553 |
| GSE43922 | Down | -0.0774383686 |
| GSE24585 | Up | 0.0122784830 |
| GSE37065 | Down | -0.1220880622 |
| GSE28863_A1 | Up | 0.0728232824 |
| GSE28863_A2 | Down | -0.4528390682 |
| GSE28863_A3 | Down | -0.0071622995 |
| GSE28863_A4 | Down | -0.2834082963 |
| GSE48662 | Up | 0.1444468645 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037633 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044546 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050495 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
